The Spencer lab has collaborated on two new papers which have come out recently:
A SIMPLI (Single-cell Identification from MultiPLexed Images) approach for spatially resolved tissue phenotyping at single-cell resolution: A software pipeline, named SIMPLI, for end-to-end analysis of Imaging Mass Cytometry data (software can be found here). Led by Michele Bortolomeazzi, a collaboration with the Ciccarelli lab at Crick.
Disrupted Peyer’s patch microanatomy in COVID-19 including germinal centre atrophy independent of local virus: Covid-19 infection disrupts the Peyer’s patch of the GI tract, regardless of the levels of virus in that location, suggesting the virus impacts the body’s ability to mount an effective intestinal immune response. Led by Silvia Cellone Trevelin, a collaboration with the Neil lab at KCL.