Read the article here: https://www.biorxiv.org/content/10.1101/2021.12.17.473179v1

A new pre-print from our lab in collaboration with the Neil lab at KCL has gone live today. In it, analysis of post-mortem tissues from the gastrointestinal tract of patients who died with COVID-19 showed that virus was present in epithelium and lamina propria macrophages, but not in lymphoid tissues of patients who had PCR-confirmed infection of the GI tract. Germinal centres were disrupted, as were the delineation of B cell and T cell zones, leading to reduced potential for B- and T-cell interaction. These observations suggest the ability to mount an intestinal immune response to COVID-19 is compromised.